Anorectics. Indicated for the treatment of people with a body mass index (BMI) less than or greater than 30 kg / m2 and who have not responded to a diet. Especially for those patients with diabetes, heart disease and hypertension.
The clobenzorex, after oral administration is well absorbed from the gastrointestinal tract, reaches its maximum concentration (Cmax) of one to one and a half after its administration and its concentration varies from 8 to 47 ng / ml. It is excreted in the urine, being one of the main metabolites amphetamine (15% of the administered dose) and p-hidroxiclobenzorex (1.5 to 6% of the administered dose).The clobenzorex is a sympathomimetic amine with pharmacological activity similar to that of other drugs used to treat obesity. It acts on the ventrolateral nucleus of the hypothalamus, increasing the release of norepinephrine and dopamine, and decreases its recapture in presynaptic nerve endings, above, has the effect of increasing concentrations of norepinephrine. Norepinephrine decreases appetite, activating the receptor to-4 And ß1 in the hypothalamic nuclei.
Not be given to patients hypersensitive to the components of the formula.Not be given to elderly people or children under 12 years.Not be given to patients with:-- Pulmonary arterial hypertension or severe.-- Psychiatric disorders, including anorexia nervosa and depression.-- Advanced arteriosclerosis.-- Hyperthyroidism.-- Prostatic hypertrophy or obstructive disease of the urinary tract.-- Antidepressants or monoamine oxidase inhibitors (MAOIs).-- History of cardiovascular or cerebrovascular disease.-- Background or who are prone to drug and / or alcohol.
Patients on a regimen of MAOIs must stay at least 15 days before drug administration to start treatment with clobenzorex, because it may cause hypertensive crisis. Clobenzorex should not be administered in partnership with other centrally acting anorectic agent, increasing the risk of causing pulmonary hypertension and the consequences can be deadly. The prescribing physician before clobenzorex should exclude secondary organic causes of obesity. During therapy is recommended include dietary, medical and psychotherapeutic. Do not stop treatment abruptly, unless because of an adverse reaction so warrant. Medication administration at night can cause nervousness and insomnia.
RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION
It should not be used during pregnancy or lactation.
Have been reported cases of pulmonary arterial hypertension, severe disease with life threatening risks. One symptom is: the occurrence or aggravation of exertional dyspnea in this case should be discontinued treatment immediately.
Central nervous system: Clobenzorex Prolonged use may develop drug tolerance, dependence and withdrawal. The most common adverse reactions are: psychotic reactions, or psychosis, depression, nervousness, agitation, sleep disturbances and dizziness. Seizures have occasionally been reported, headache.
Cardiovascular effects: Most often include tachycardia, palpitations, hypertension and chest pain. Have been rarely reported cardiovascular or cerebrovascular accidents, particularly stroke, angina, myocardial infarction, heart failure and cardiac arrest in patients treated with anorectic agents.
Gastrointestinal effects: Dry mouth and constipation.
Effect on Urinary Tract Dysuria, urinary retention.
DRUG INTERACTIONS AND OTHER GENDER
Clobenzorex not be administered concomitantly with:-- Antidepressants or MAO inhibitors (MAOIs).-- Guanethidine or its derivatives, since both share the same active site of action. Guanethidine and its derivatives could be displaced by deleting its antihypertensive effect.-- Phenylethylamine derivatives, appetite suppressants, and tricyclic antidepressants may potentiate the effects of the latter.-- Sympathomimetic agents and general anesthetics, can cause arrhythmias.It should be administered 14 days after stopping treatment with an MAOI, because it may cause hypertensive crisis.
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Online pharmacy Medicines Mexico shipping terms and conditions.
Our team endeavors to process all orders and ship within 72 business hours. All credit card and electronic check payments for your Mexico medicine take 24 to 48 hours to be approved by our Payment Processor; upon verification your order will be processed. If there are any problems with your order, we will contact you, so please ensure the email address and phone number you provide is correct, and that any spam filtering software you use accepts email from www.medicinesmexicorx.com
We offer Mex Post Express Shipping as an option. This option costs from $24.95 depending on the quantity of medications in your order (up to 9 medications). This option requires a customer signature on delivery. For all other locations Express Shipping is $39.95. All packages are shipped in plain packaging to guarantee your privacy. All packages are sent by parcel express mail from Mexico. Some parcels require a signature upon delivery at our discretion. There are no other handling fees, drug dispensing fees, or Mexican customs charges. If two or more people are ordering their prescription drugs from the same address at the same time, you will be billed for only one shipping charge from our Mexico pharmacy, up to our maximum order quantities limited by customs to 90 day supply. We are able to provide a tracking number on your express shipping parcels. If after 30 business days your order has not arrived, first check with your local postal office to ensure that your package is not being held for pick-up. If you still have problems, please contact us by email and we will attempt to assist you.
If no one is at home at the time of delivery, the status of you order on the Postal System will be updated to “Notice Left” which means USPS attempted to deliver your item and a notice was left because an authorized recipient was not available. You may arrange redelivery by visiting or calling 800-ASK-USPS, or may pick up the item at the Post Office indicated on the notice. If this item is unclaimed after five days then it will be returned to the sender. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).
Note that on Holidays season, the Mexican Postal, USA and other countries will be extra busy; therefore a delay is expected in packages shipped during this season. You will need to consider as well the Mexican holidays. We appreciate your understanding, our customer service will be happy to assist you and available to inform you the latest status on your existing order shipped, you can always contact us at Toll Free number or email address.
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Due to government regulations and the possibility of tampering with medications, returns cannot be accepted. In case your package is returned due to no one was available to sign for it. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).
How to find the online pharmacy drug you need.
There are many more medications available in Mexico that are not listed on our website. If you can’t find the Mexican drug or medication you require, please contact us and we may be able to help. Some products are listed only in a single dosage size or medicine type, but may be available in other dosages and forms. Our experienced Mexican pharmacy Pharmacists will do their best to accommodate your requirements. Please always specify the chemical name of the medication (and any applicable brand name) with all inquiries. Please feel free to ask about ANY drug. We will reply promptly to your request.
What you should know about brand and generic drug alternates.
Prescription drugs are a costly medical expense, especially for the elderly, those who are chronically ill and those with no or minimal drug coverage on their Health Insurance. However, each state in America has a law that allows pharmacists to substitute less expensive generic drugs for many brand name products. Depending on your prescription needs, your savings could be very significant. Before you talk with your doctor or pharmacist about switching, there are things you should know about generic drugs.
What is the difference between a generic and brand name drug?
Nothing except for the name, packaging, and the price, a generic drug is called by its chemical name; manufacturers assign their own brand name. The generic products have the same ingredients. Standard practice and most state laws require that a generic drug be generically equivalent to its brand name counterpart. That is, it must have the same active ingredients, strength, and dosage form, be it a pill, liquid, or injection. The generic drug also must be therapeutically equivalent. It must be the same drug chemically and have the same medical effect.
Do all drugs have generic equivalents?
No. Some drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.
Will my doctor automatically prescribe generic drugs?
It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate or to define the chemical name for the prescription. This will ensure you are purchasing the correct Mexico drug. Generic products will be as effective and less costly. Or, you can order only brand name products if you wish. www.MedicinesMexicoRX.com Mexico pharmacy offers a wide selection of both Brand Name & Generic Mexico medicine. Our Mexican generic drugs are of the highest quality, selected only from the most reputable manufacturers, and are safe to replace brand name medications costing much more.
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